Position Details
IRCCS San Raffaele Scientific Institute in Milan–Italy, is looking for a young motivated researcher to join the Cell Adhesion Laboratory directed by Prof. Ivan de Curtis. The candidate will work on a project aimed at the analysis of molecular-cellular mechanisms implicated in tumor cell invasion, to identify new targets to interfere with the formation of metastases. The project financed by AIRC is dealing with the functional characterization of a molecular network that regulates the protrusive activity of invasive tumor cells (de Curtis I, 2021, Trends Cell Biol, doi: 10.1016/j.tcb.2020.12.002; Pehkonen H, de Curtis I, 2021, Oncogene doi: 10.1038/s41388-021-02048-1). This protein network includes the scaffold proteins Liprin-a1 and ERC1 (Ribolla, de Curtis I, 2025, Commun Biol, doi: 10.1038/s42003-025-08470-5) and regulatory enzymes (Ramella, de Curtis, 2024, iScience doi: 10.1016/j.isci.2024.109440; Ripamonti M, de Curtis I, 2022, Commun Biol doi: 10.1038/s42003-022-03989-3) undergoin...