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Senior Scientist, Stem Cell Model Engineering( Contract)

Company: Amgen

Location: burnaby, London

Posted: June 08, 2026

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Position Details

Sr. Scientist, Stem Cell Model Engineering

Join the Predictive Biology team as a hands‑on scientist focused on building genetically engineered human induced pluripotent stem cell (iPSC) models to support target discovery, target validation, and mechanism‑of‑action studies. You will troubleshoot complex systems, improve current workflows, and help drive the next wave of innovation in human stem cell model engineering.

Key Responsibilities

  • Develop genetically defined iPSC model systems, including reporter, tagged, loss‑of‑function, disease‑relevant, inducible, or otherwise perturbable models.
  • Define and interpret fit‑for‑purpose validation strategies to determine whether engineered models are suitable for downstream biological studies.
  • Identify, troubleshoot, and solve technical and biological failure modes, including poor editing outcomes, clonal artifacts, expression instability, differentiation defects...