Do you want to contribute to improving human health?

Come and join us at the Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm. In the research group led by Laura Baranello, we are particularly interested in the molecular mechanisms defining the crosstalk between transcription, DNA topology and chromatin folding, with the aim to design improved strategies for anti-cancer treatment.

Division

The Baranello Lab - Drawing from our expertise in the fields of topoisomerase and cancer biology, we aim to answer fundamental questions about how transcription, replication and DNA topology are functionally coordinated in human cells. We use state-of-the-art approaches to assess transcriptomic, epigenomic and replisomic profiles, as well as molecular biology, advanced microscopy and drug screens to understand how topoisomerase regulation affects fundamental nuclear processes (key lab references: Baranello...